Nale?y zachowa? ostro?no?? podczas stosowania preparatu z lekami wp?ywaj?cymi na aktywno?? izoenzymu 3A4 cytochromu P450. Leki hamuj?ce aktywno?? tego izoenzymu (np.Preparatu nie nale?y stosowa? bez równoleg?ego leczenia depresji lub l?ku zwi?zanego z depresj?. W okresie stosowania preparatu mo?e ujawni? si? wcze?niej istniej?ca depresja.Regula
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